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Magical Realist
Apr 10, 2025 05:10 AM
(This post was last modified: Apr 10, 2025 05:17 AM by Magical Realist.)
Quote:Again, when "transferred into an egg"... just like sperm DNA. Specialized cells don't magically become totipotent on their own. You have to seed existing totipotent stem cells.
They're as totipotent as zygotes are when used for cloning. There's simply no debating this.
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Syne
Apr 10, 2025 11:16 PM
You're a scientifically illiterate moron.
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Secular Sanity
Apr 11, 2025 01:05 AM
Well, we haven’t done it to a human yet, but to clone, you take an egg cell from a donor and remove its nucleus (goodbye original DNA). Insert the nucleus from a somatic cell (like a skin cell) into the enucleated egg. Stimulate the egg to divide by using electricity or chemicals (no sperm needed) → it starts behaving like a fertilized egg.
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Syne
Apr 11, 2025 02:18 AM
(This post was last modified: Apr 11, 2025 02:18 AM by Syne.)
Again, for the third time now. When "transferred into an egg"... just like sperm DNA. You're just using a different source of DNA. You're not changing the nature of totipotent and specialized cells.
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Magical Realist
Apr 11, 2025 03:36 AM
(This post was last modified: Apr 11, 2025 04:14 AM by Magical Realist.)
An unfertilized ovum isn't totipotent either. It is a specialized cell like all other cells. It only becomes totipotent when it's united with a sperm cell. Same with somatic cells. They aren't totipotent and then become totipotent when used for cloning. Educate yourself before running your ignorant foul-assed mouth.
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Syne
Apr 11, 2025 11:20 PM
You have to use a germ cell (ovum) and add DNA to get a totipotent cell. Germ cells are the only precursors to totipotent cells in humans. Somatic cells only contribute DNA. They do not magically become totipotent.
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Magical Realist
Apr 12, 2025 01:09 AM
Quote:You have to use a germ cell (ovum) and add DNA to get a totipotent cell.
Yep..just like with a zygote. A specialized cell (ovum) becomes a totipotent cell with the addition of DNA from a sperm cell. No difference whatsoever.
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Syne
Apr 12, 2025 01:12 AM
(This post was last modified: Apr 12, 2025 01:15 AM by Syne.)
You can't do it without a germ cell. Big difference from the ridiculous claim that ordinary somatic cells can magically become totipotent.
But nice red herring. Remember, we were taking about embryos vs somatic cells.
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Magical Realist
Apr 12, 2025 01:24 AM
"a somatic cell can become totipotent under certain conditions, particularly through a process called somatic cell nuclear transfer (SCNT), also known as cloning. In SCNT, the nucleus of a somatic cell is transferred into an enucleated oocyte, which then can reprogram the somatic nucleus to a totipotent state, allowing the development of a complete organism."--AI Google
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Syne
Apr 12, 2025 02:10 AM
Again, requiring a germ cell.
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