Does Oral Sex Prevent Miscarriage?

#1
https://www.acsh.org/news/2019/04/04/doe...guys-13933

INTRO: A new study that says oral sex can prevent miscarriage predictably has gone viral, thanks mostly to the rather excitable British tabloids. But is it true? If it is, the study doesn't even come close to confirming the hypothesis.

The notion that oral sex can prevent miscarriage isn't as far-fetched as it sounds. The idea is that regular exposure to her partner's semen will make a woman less likely to mount an immunological attack on the baby. Other previous research has suggested that exposure to semen -- either through oral or unprotected vaginal sex -- was associated with a lower risk of preeclampsia. The plausible underlying explanation for these disparate phenomena is maternal immunological tolerance to the father's semen.

The current research, which was published in the Journal of Reproductive Immunology, examined 97 women with recurring miscarriages ("cases") and 137 women without miscarriages ("controls"). They found that women who performed oral sex had 50% lower odds of miscarriage than women who did not. But there are some serious shortcomings in the paper... (MORE)
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#2
Quote:serious shortcomings 

Big Grin
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#3
When I first saw the subject line, my response was "Well, duh!" I mean, oral sex isn't going to get a woman pregnant and no pregnancy means no miscarriage.

But the thesis that oral sex might reduce immunological sensitivity that might attack an unborn baby doesn't sound that outlandish.

I'm still not convinced though. But the article that CC posted didn't convince me the other way either.
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#4
Pass. Whatever that might mean.
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#5
Quote:A team from the University of Adelaide has also investigated to see if men who have fathered pregnancies which have ended in miscarriage or pre-eclampsia had low seminal levels of critical immune modulating factors such as TGF-beta. The team has found that certain men, dubbed "dangerous males", are several times more likely to father pregnancies that would end in either pre-eclampsia or miscarriage. Among other things, most of the "dangerous males" seemed to lack sufficient levels of the seminal immune factors necessary to induce immunological tolerance in their partners.

https://en.wikipedia.org/wiki/Pre-eclamp..._tolerance

Transforming growth factor (TGF)-β1 present in seminal plasma triggers a female immune response favorable for implantation. TGF-beta influences salivary gland development and plays an important biological role in maintaining homeostasis within the oral tissues.

As the theory of immune intolerance as a cause of pre-eclampsia has become accepted, women who with repeated pre-eclampsia, miscarriages, or in vitro fertilization failures could potentially benefit from exposure to TGF-beta via salvia prior to intercourse.

"Dangerous males" with low levels of TGF-beta in seminal plasma should therefore perform oral sex and moisten their fingers with salvia applying it to the vaginal wall before intercourse. Fifteen minutes is the minimum requirement for exposure.

More research is needed to confirm the benefits of exposure to TGF-beta via salvia prior to intercourse.  Wink
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