Aug 29, 2018 07:36 AM
https://www.eurekalert.org/pub_releases/...082218.php
EXCERPT: One of the most intriguing questions about the human brain is also one of the most difficult for neuroscientists to answer: What sets our brains apart from those of other animals? "We really don't understand what makes the human brain special," said Ed Lein, Ph.D., Investigator at the Allen Institute for Brain Science. "Studying the differences at the level of cells and circuits is a good place to start, and now we have new tools to do just that."
. . . [Gábor] Tamás and University of Szeged doctoral student Eszter Boldog dubbed these new cells "rosehip neurons" -- to them, the dense bundle each brain cell's axon forms around the cell's center looks just like a rose after it has shed its petals, he said. The newly discovered cells belong to a class of neurons known as inhibitory neurons, which put the brakes on the activity of other neurons in the brain.
The study hasn't proven that this special brain cell is unique to humans. But the fact that the special neuron doesn't exist in rodents is intriguing, adding these cells to a very short list of specialized neurons that may exist only in humans or only in primate brains.
The researchers don't yet understand what these cells might be doing in the human brain, but their absence in the mouse points to how difficult it is to model human brain diseases in laboratory animals, Tamás said. One of his laboratory team's immediate next steps is to look for rosehip neurons in postmortem brain samples from people with neuropsychiatric disorders to see if these specialized cells might be altered in human disease....
MORE: https://www.eurekalert.org/pub_releases/...082218.php
EXCERPT: One of the most intriguing questions about the human brain is also one of the most difficult for neuroscientists to answer: What sets our brains apart from those of other animals? "We really don't understand what makes the human brain special," said Ed Lein, Ph.D., Investigator at the Allen Institute for Brain Science. "Studying the differences at the level of cells and circuits is a good place to start, and now we have new tools to do just that."
. . . [Gábor] Tamás and University of Szeged doctoral student Eszter Boldog dubbed these new cells "rosehip neurons" -- to them, the dense bundle each brain cell's axon forms around the cell's center looks just like a rose after it has shed its petals, he said. The newly discovered cells belong to a class of neurons known as inhibitory neurons, which put the brakes on the activity of other neurons in the brain.
The study hasn't proven that this special brain cell is unique to humans. But the fact that the special neuron doesn't exist in rodents is intriguing, adding these cells to a very short list of specialized neurons that may exist only in humans or only in primate brains.
The researchers don't yet understand what these cells might be doing in the human brain, but their absence in the mouse points to how difficult it is to model human brain diseases in laboratory animals, Tamás said. One of his laboratory team's immediate next steps is to look for rosehip neurons in postmortem brain samples from people with neuropsychiatric disorders to see if these specialized cells might be altered in human disease....
MORE: https://www.eurekalert.org/pub_releases/...082218.php