Article Ozempic face’ & hair loss: what evidence is there for weight-loss drug side-effects?

[C C]

https://www.theguardian.com/science/2026...empic-face

EXCERPTS (each incomplete): Digestive problems. Nausea, vomiting, diarrhoea and constipation – there is no shortage of reports of gut-related problems among people using GLP-1 medications. But while unpleasant, they are well known and have been documented in clinical trials...

Eye conditions More than one eye condition has been flagged in relation to GLP-1 medications. Last year, a study revealed people with diabetes who use the drugs could face double the risk of developing age-related macular degeneration, while reports based on adverse event reporting systems and matched cohort studies have suggested some GLP-1 medications have the potential to cause an eye disorder called non-arteritic anterior ischaemic optic neuropathy. This condition can cause sudden – and permanent – sight loss...

Pregnancies. There have been numerous reports of unexpected pregnancies among those using GLP-1 medications...

Ozempic face. Social media is awash with people reporting a dramatic change in facial appearance after using GLP-1 medications, including sunken eyes, wrinkles, facial ageing and sagging skin...

Hair thinning. Hair loss hit the headlines this week after research suggested it could be associated with the use of GLP-1 medications in adults with type 2 diabetes. It is not the first time a potential link has been mooted...

Ozempic foot. So-called Ozempic foot – a term for a bony appearance of the feet, with some people also reporting foot pain – has been claimed to be a side-effect of GLP-1 medications, but it is not found in patient information leaflets... (MORE - missing details)

[Magical Realist]

Nausea, vomiting, diarrhoea and constipation – there is no shortage of reports of gut-related problems among people using GLP-1 medications.

Yes..a well-know risk factor in taking any anti-diabetic med, including Metformin.

Last year, a study revealed people with diabetes who use the drugs could face double the risk of developing age-related macular degeneration, while reports based on adverse event reporting systems and matched cohort studies have suggested some GLP-1 medications have the potential to cause an eye disorder called non-arteritic anterior ischaemic optic neuropathy. This condition can cause sudden – and permanent – sight loss...

That's an interesting one. Don't know why that'd be.

There have been numerous reports of unexpected pregnancies among those using GLP-1 medications...

"Immaculate conceptions" are not uncommon among those who suddenly have in increase in sexual activity due to weight loss.

Social media is awash with people reporting a dramatic change in facial appearance after using GLP-1 medications, including sunken eyes, wrinkles, facial ageing and sagging skin...

That's just the effect of losing weight in general. Once our skin has been stretched out due to obesity, it tends to sag and get wrinkly when we get thin.

Hair loss hit the headlines this week after research suggested it could be associated with the use of GLP-1 medications in adults with type 2 diabetes. It is not the first time a potential link has been mooted...

Not sure why a drug that actually reduces type 2 diabetes would have a hair-loss side effect. Might just be a natural anxiety side effect from increased scrutiny over one's body as one loses weight.

So-called Ozempic foot – a term for a bony appearance of the feet, with some people also reporting foot pain – has been claimed to be a side-effect of GLP-1 medications, but it is not found in patient information leaflets

Hmmm...Fat loss = bony appearance?

[Syne]

Loss of muscle mass, lack of sufficient nutrition, and rapid weight loss likely cause all these.

[C C]

Highlights how slow the outcomes of conventional dieting are compared to this (sans eating disorders like anorexia). How in the past, rapid weight loss of this magnitude and its visible effects would be associated with people who had cancer or some thyroid condition, etc. Ergo, the "uncanny feeling" reaction that something dire must be afoot.

Erin Moriarty's radical facial changes had people speculating that she was either taking the drug or had undergone plastic surgery at the level of Michael Jackson. In reality, she was suffering from recently acquired Grave's disease. So again: that lingering, classic, scary connection to illness because regular regimes for losing weight simply did not compare to this (were too gradual and erratically successful).