Mar 23, 2021 11:25 PM
https://www.medpagetoday.com/meetingcoverage/endo/91772
INTRO: Many transgender youth will likely face a higher risk of poor cardiometabolic outcomes, according to new research. An analysis of over 4,000 American youth diagnosed with gender dysphoria found these patients had a nearly two times higher chance of developing metabolic syndrome compared with youth without gender dysphoria, reported Anna Valentine, MD, of the University of Colorado Anschutz Medical Campus in Aurora.
In her presentation at the Endocrine Society's virtual ENDO 2021 meeting, Valentine explained that these youth -- including both those assigned male at birth and female at birth -- also had a significantly higher odds of developing dyslipidemia compared with cisgender youth.
For only transgender youth assigned female at birth, the researchers found that these individuals had a significantly higher odds of developing overweight or obesity. They also had a nearly two times higher chance of being diagnosed with polycystic ovary syndrome compared with cisgender female youth.
On the other hand, transyouth did not have an excess risk of hypertension, dysglycemia, or liver dysfunction.
A number of different mechanisms could underlie these findings, Valentine explained during a press conference. "We know that some youth with gender dysphoria have higher rates of overweight and obesity, and that having overweight and obesity itself increases your risk of having other diagnoses." It is also known that "youth with gender dysphoria have higher rates of mental health comorbidities ... as well as getting less physical activity," she said.
"And they also may be taking medication that could all influence their cardiometabolic health," she added... (MORE)
INTRO: Many transgender youth will likely face a higher risk of poor cardiometabolic outcomes, according to new research. An analysis of over 4,000 American youth diagnosed with gender dysphoria found these patients had a nearly two times higher chance of developing metabolic syndrome compared with youth without gender dysphoria, reported Anna Valentine, MD, of the University of Colorado Anschutz Medical Campus in Aurora.
In her presentation at the Endocrine Society's virtual ENDO 2021 meeting, Valentine explained that these youth -- including both those assigned male at birth and female at birth -- also had a significantly higher odds of developing dyslipidemia compared with cisgender youth.
For only transgender youth assigned female at birth, the researchers found that these individuals had a significantly higher odds of developing overweight or obesity. They also had a nearly two times higher chance of being diagnosed with polycystic ovary syndrome compared with cisgender female youth.
On the other hand, transyouth did not have an excess risk of hypertension, dysglycemia, or liver dysfunction.
A number of different mechanisms could underlie these findings, Valentine explained during a press conference. "We know that some youth with gender dysphoria have higher rates of overweight and obesity, and that having overweight and obesity itself increases your risk of having other diagnoses." It is also known that "youth with gender dysphoria have higher rates of mental health comorbidities ... as well as getting less physical activity," she said.
"And they also may be taking medication that could all influence their cardiometabolic health," she added... (MORE)