http://www.sciencemag.org/news/2018/02/a...er-science
EXCERPT: . . . For decades, lab animals such as rodents and fish have lived in barren enclosures: a small plastic box, few—if any—companions, and little else. The smaller the number of variables, the thinking went, the greater the accuracy of the experiment. But a growing number of studies suggests that this approach may have backfired. Only one in nine drugs that works in animals ever succeeds in human clinical trials, and labs often struggle to reproduce one another's results. Could the environment these creatures live in be part of the problem?
That's what a new group of advocates argues. "We're trying to control these animals so much, they're no longer useful," says Joseph Garner, a behavioral scientist who runs a program to improve the value and welfare of lab animals at Stanford University in Palo Alto, California. "If we want animals to tell us about stuff that's going to happen in people, we need to treat them more like people...."
MORE: http://www.sciencemag.org/news/2018/02/a...er-science
EXCERPT: . . . For decades, lab animals such as rodents and fish have lived in barren enclosures: a small plastic box, few—if any—companions, and little else. The smaller the number of variables, the thinking went, the greater the accuracy of the experiment. But a growing number of studies suggests that this approach may have backfired. Only one in nine drugs that works in animals ever succeeds in human clinical trials, and labs often struggle to reproduce one another's results. Could the environment these creatures live in be part of the problem?
That's what a new group of advocates argues. "We're trying to control these animals so much, they're no longer useful," says Joseph Garner, a behavioral scientist who runs a program to improve the value and welfare of lab animals at Stanford University in Palo Alto, California. "If we want animals to tell us about stuff that's going to happen in people, we need to treat them more like people...."
MORE: http://www.sciencemag.org/news/2018/02/a...er-science