Sep 15, 2026 04:53 PM
(This post was last modified: Sep 15, 2026 06:54 PM by C C.)
Drug improves sexual function for patients with depression, study finds
https://www.eurekalert.org/news-releases/1143897
INTRO: Patients with major depressive disorder (MDD) and an inadequate response to standard antidepressants who received an add- on treatment with the drug lumateperone saw significantly improved sexual function, found a new study led by a University of Virginia School of Medicine researcher.
In a study of 480 patients, significant improvements in sexual function were seen in patients who were randomized to receive a daily 42 mg dose of lumateperone added to their antidepressant therapy compared with patients whose additional treatment was a harmless placebo. Improvements were seen across multiple patient groups including those with baseline sexual dysfunction, women, younger and older adults as well as across various aspects of sexual functioning (desire, arousal, orgasm and pleasure).
Approximately 68% of patients with major depressive disorder have sexual dysfunction, and the sexual side effects of antidepressant medications are a leading reason patients stop treatment. Lead researcher Anita H. Clayton, MD, a psychiatrist at UVA Health, hailed the findings as an important step forward in the management of sexual dysfunction in patients with depression... (MORE - no ads)
What can go wrong with genital fillers?
https://theconversation.com/men-and-wome...ong-289872
EXCERPTS: Fillers are everywhere now – smoothing lines, plumping cheeks, adding volume around the eyes, nose and lips in clinics up and down the country. But some men are now having fillers injected into their penises to increase their size. [...] Research is limited when it comes to the risks, but a recent study estimated that complications occur in about 9% of men receiving hyaluronic acid fillers.
These complications can include bruising and swelling, as well as lumps and nodules. More serious problems include skin irritation, tissue breakdown and infections. The timing of these problems can vary. Bleeding and bruising tend to occur during the first week or two. Nodules may appear around the third week. Infections often appear around six or seven weeks after treatment, although they can occur years later.
In severe cases, infection can progress rapidly to multiple organ failure. There have also been cases of tissue death requiring part of the penis to be removed. And in March, social media influencer Igho Ubiribo, known as “Ego”, died from a pulmonary embolism following a penis filler procedure in Thailand.
Hyaluronic acid is not the only way men are trying to increase penis size. Another option involves taking fat from elsewhere in the body and injecting it into the penis. This carries its own risks. These include injecting fat into the wrong area, as well as swelling and bruising. Men can also develop lumps or deformities caused by uneven fat distribution or the death of the injected fat.
There is also the risk of infection with bacteria such as S aureus or E coli. In the most serious cases, tissue can die or the patient can die from a fat embolism.
Another treatment being offered for sexual enhancement is PRP, or platelet-rich plasma. These injections are not just marketed to men. The so-called “P-shot”, or priapus shot, is promoted for men, while the “O-shot”, or orgasm shot, is marketed to women... (MORE - missing details)
https://www.eurekalert.org/news-releases/1143897
INTRO: Patients with major depressive disorder (MDD) and an inadequate response to standard antidepressants who received an add- on treatment with the drug lumateperone saw significantly improved sexual function, found a new study led by a University of Virginia School of Medicine researcher.
In a study of 480 patients, significant improvements in sexual function were seen in patients who were randomized to receive a daily 42 mg dose of lumateperone added to their antidepressant therapy compared with patients whose additional treatment was a harmless placebo. Improvements were seen across multiple patient groups including those with baseline sexual dysfunction, women, younger and older adults as well as across various aspects of sexual functioning (desire, arousal, orgasm and pleasure).
Approximately 68% of patients with major depressive disorder have sexual dysfunction, and the sexual side effects of antidepressant medications are a leading reason patients stop treatment. Lead researcher Anita H. Clayton, MD, a psychiatrist at UVA Health, hailed the findings as an important step forward in the management of sexual dysfunction in patients with depression... (MORE - no ads)
What can go wrong with genital fillers?
https://theconversation.com/men-and-wome...ong-289872
EXCERPTS: Fillers are everywhere now – smoothing lines, plumping cheeks, adding volume around the eyes, nose and lips in clinics up and down the country. But some men are now having fillers injected into their penises to increase their size. [...] Research is limited when it comes to the risks, but a recent study estimated that complications occur in about 9% of men receiving hyaluronic acid fillers.
These complications can include bruising and swelling, as well as lumps and nodules. More serious problems include skin irritation, tissue breakdown and infections. The timing of these problems can vary. Bleeding and bruising tend to occur during the first week or two. Nodules may appear around the third week. Infections often appear around six or seven weeks after treatment, although they can occur years later.
In severe cases, infection can progress rapidly to multiple organ failure. There have also been cases of tissue death requiring part of the penis to be removed. And in March, social media influencer Igho Ubiribo, known as “Ego”, died from a pulmonary embolism following a penis filler procedure in Thailand.
Hyaluronic acid is not the only way men are trying to increase penis size. Another option involves taking fat from elsewhere in the body and injecting it into the penis. This carries its own risks. These include injecting fat into the wrong area, as well as swelling and bruising. Men can also develop lumps or deformities caused by uneven fat distribution or the death of the injected fat.
There is also the risk of infection with bacteria such as S aureus or E coli. In the most serious cases, tissue can die or the patient can die from a fat embolism.
Another treatment being offered for sexual enhancement is PRP, or platelet-rich plasma. These injections are not just marketed to men. The so-called “P-shot”, or priapus shot, is promoted for men, while the “O-shot”, or orgasm shot, is marketed to women... (MORE - missing details)
