Jun 17, 2026 08:49 PM
Lifestyle factors may influence prostate cancer risk in Indian men
https://www.eurekalert.org/news-releases/1132597
EXCERPT: The analysis revealed that coffee consumption and meat intake were associated with lower odds of prostate cancer. After adjustment for potential confounding factors, coffee consumption was associated with approximately 65% lower odds of prostate cancer, while meat consumption was associated with approximately 48% lower odds.
In contrast, no statistically significant associations were observed for alcohol consumption, tobacco chewing, smoking, tea intake, or farming occupation after adjustment for other variables. Although smoking and tobacco use initially appeared to be associated with higher odds of prostate cancer, these relationships were no longer statistically significant in the adjusted analysis.
The investigators also discussed several biological mechanisms that could potentially explain the observed findings. Coffee contains bioactive compounds such as cafestol, kahweol, caffeine, and antioxidant polyphenols that have been studied for anti-inflammatory, antioxidant, and anti-cancer properties. Certain compounds found in meat, including trans-vaccenic acid, have also been linked to immune responses that may influence cancer biology.
However, the authors emphasize that the relationship between diet and prostate cancer remains complex. Previous studies have produced conflicting findings regarding the effects of coffee, meat, tea, alcohol, and tobacco on prostate cancer risk. The researchers note that their study evaluated overall consumption patterns and did not distinguish between different types of meat, preparation methods, or levels of intake... (MORE - no ads)
PAPER: http://dx.doi.org/10.18632/oncoscience.657
https://www.eurekalert.org/news-releases/1132597
EXCERPT: The analysis revealed that coffee consumption and meat intake were associated with lower odds of prostate cancer. After adjustment for potential confounding factors, coffee consumption was associated with approximately 65% lower odds of prostate cancer, while meat consumption was associated with approximately 48% lower odds.
In contrast, no statistically significant associations were observed for alcohol consumption, tobacco chewing, smoking, tea intake, or farming occupation after adjustment for other variables. Although smoking and tobacco use initially appeared to be associated with higher odds of prostate cancer, these relationships were no longer statistically significant in the adjusted analysis.
The investigators also discussed several biological mechanisms that could potentially explain the observed findings. Coffee contains bioactive compounds such as cafestol, kahweol, caffeine, and antioxidant polyphenols that have been studied for anti-inflammatory, antioxidant, and anti-cancer properties. Certain compounds found in meat, including trans-vaccenic acid, have also been linked to immune responses that may influence cancer biology.
However, the authors emphasize that the relationship between diet and prostate cancer remains complex. Previous studies have produced conflicting findings regarding the effects of coffee, meat, tea, alcohol, and tobacco on prostate cancer risk. The researchers note that their study evaluated overall consumption patterns and did not distinguish between different types of meat, preparation methods, or levels of intake... (MORE - no ads)
PAPER: http://dx.doi.org/10.18632/oncoscience.657