Article  Is Vitamin D completely useless now?

#1
C C Offline
Or maybe there's little point in paying attention to anything outputted by the soft or human-focused sciences, one way or the other. "If you don't like something in nutritional research, just wait a few months or years and it will change."
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Will Vitamin D Go the Way of Cod Liver Oil?
https://www.mcgill.ca/oss/article/critic...-liver-oil

EXCERPT: The subjects were followed for five years and filled out annual questionnaires about numerous health outcomes. Given that some other studies, albeit much smaller ones, had shown benefits associated with Vitamin D supplements, the results were surprising.

In VITAL, Vitamin D supplements did not prevent cardiovascular disease or cancer, did not improve stroke outcomes, did not improve cognition, did not reduce atrial fibrillation, did not change body composition or reduce knee pain. A bit of “data mining” did find fewer cases of advanced cancers detected in the Vitamin D group. An even greater surprise came when the data were analyzed for risk of fractures, something that was expected to be reduced by the bone-strengthening effect of Vitamin D. It wasn’t.

There was no reduction in risk of any kind of fracture, not even in subjects who were taking 1,200 mg of supplemental calcium. Furthermore, not even individuals considered as being “deficient,” based on blood levels of Vitamin D below 20 nanograms per millilitre, were found to benefit from supplements. This would call into question the widespread testing for Vitamin D that usually prompts advice to take a supplement if the level is below 30 nanograms per millilitre. Based on VITAL, there is little evidence for taking Vitamin D supplements, but there is no harm either... (MORE - missing details)
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#2
Magical Realist Offline
Damn it! No more than 2 hours ago I bought some more Vitamin D supplements at the store. I'm woefully out of sync with the big sciency spin machine.
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#3
Syne Offline
No mention of magnesium in that article. 9_9

Magnesium is Required to Activate vitamin D.
Magnesium is needed to move vitamin D around in the blood and to activate vitamin D. Magnesium deficiency can also reduce active vitamin D (1,25 dihydroxyvitamin D) levels and impair parathyroid hormone response.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC7861592/

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