Jun 9, 2025 11:27 PM
https://www.ucsf.edu/news/2025/06/430141...e-you-live
PRESS RELEASE: In one of the largest and most comprehensive studies of its kind, a research team led at UC San Francisco has identified the regions where dementia occurs most often.
What They Discovered. Using the Mid-Atlantic* as the basis for comparison, researchers found that dementia rates were 25% higher in the Southeast.
** The Northwest*** and Rocky Mountains**** were both 23% higher, and the South***** was 18% higher.
The Southwest, which includes California, was 13% higher; while the Northeast, which includes New York, was 7% higher.
These differences remained when researchers accounted for factors like age, race, and cardiovascular disease. This includes rural areas, where medical care may be less accessible, compared to urban areas.
What’s Next: “The study underscores the need to understand regional differences in dementia and the importance of region-specific prevention and intervention efforts,” said senior author Kristine Yaffe, MD, also of the San Francisco VA Health Care System.
First author Christina Dintica, PhD, said the next step is to investigate the factors driving these differences. “Quality of education, early life conditions, and environmental exposures may be among those factors.”
- - - footnotes - - -
*Mid-Atlantic: Del., Washington, D.C., Md., Pa., Va., W.Va., N.J.
**Southeast: Ky., Tenn., Ala., Miss.
***Northwest: Alaska, Idaho, Ore., Wash.
****Rocky Mountains: Colo., Mont., N.D., S.D., Utah, Wyo.
*****South: Ark., La., N.M., Okla., Texas.
Regions were defined by the Centers for Disease Control and Prevention. Each region comprises four to seven states.
Publication: JAMA Neurology
Other Researchers: Amber Bahorik, PhD, and John Boscardin, PhD, of UCSF; Feng Xia, PhD, of Northern California Institute for Research and Education.
Funding: Alzheimer’s Association (AARF-21-851960), National Institute on Aging (R35 AG071916), Department of Defense (W81XWH-22-1-096).
PRESS RELEASE: In one of the largest and most comprehensive studies of its kind, a research team led at UC San Francisco has identified the regions where dementia occurs most often.
What They Discovered. Using the Mid-Atlantic* as the basis for comparison, researchers found that dementia rates were 25% higher in the Southeast.
** The Northwest*** and Rocky Mountains**** were both 23% higher, and the South***** was 18% higher.
The Southwest, which includes California, was 13% higher; while the Northeast, which includes New York, was 7% higher.
These differences remained when researchers accounted for factors like age, race, and cardiovascular disease. This includes rural areas, where medical care may be less accessible, compared to urban areas.
What’s Next: “The study underscores the need to understand regional differences in dementia and the importance of region-specific prevention and intervention efforts,” said senior author Kristine Yaffe, MD, also of the San Francisco VA Health Care System.
First author Christina Dintica, PhD, said the next step is to investigate the factors driving these differences. “Quality of education, early life conditions, and environmental exposures may be among those factors.”
- - - footnotes - - -
*Mid-Atlantic: Del., Washington, D.C., Md., Pa., Va., W.Va., N.J.
**Southeast: Ky., Tenn., Ala., Miss.
***Northwest: Alaska, Idaho, Ore., Wash.
****Rocky Mountains: Colo., Mont., N.D., S.D., Utah, Wyo.
*****South: Ark., La., N.M., Okla., Texas.
Regions were defined by the Centers for Disease Control and Prevention. Each region comprises four to seven states.
Publication: JAMA Neurology
Other Researchers: Amber Bahorik, PhD, and John Boscardin, PhD, of UCSF; Feng Xia, PhD, of Northern California Institute for Research and Education.
Funding: Alzheimer’s Association (AARF-21-851960), National Institute on Aging (R35 AG071916), Department of Defense (W81XWH-22-1-096).