Oct 16, 2023 02:20 PM
https://www.sciencefocus.com/the-human-b...tile-women
EXCERPT: . . . So far, 90 women worldwide have received uterine transplants which have resulted in 49 babies. It is important to continuously monitor the development of these babies, especially as the sole goal of the uterine transplant is for a live birth of a healthy infant.
It is particularly relevant and promising to see that the babies have grown well during pregnancy, with no evidence of growth restriction, and are meeting age-appropriate neonatal and developmental milestones for the 2 years they have been monitored.
Excitingly, the first uterine transplant in the UK took place earlier this year. The patient was a 34-year-old with a genetic condition called Mayer-Rokintansky-Küster-Hauser syndrome (MRKH), which affects 1 in 5,000 women. This means she has AUFI as she was born with ovaries but no Fallopian tubes or uterus.
She wants children, but specifically she wants to give birth and have a biological relationship with her offspring. This ruled out adoption and surrogacy.
But her sister, who doesn't have MRKH – and was born with ovaries, Fallopian tubes and a uterus – wanted to donate her uterus to help enable this. She had completed her family, having had two successful uncomplicated pregnancies and given birth to two healthy babies.
Both women had to undergo significant pre-op medical and psychological preparation to ensure their health and wellbeing were optimised and the operation could be a success. The operations for both women involved major surgery which carries its own risk.
In addition, the major concern for a recipient is the possibility of the body ‘rejecting’ the donor womb. To avoid this, anti-rejection drugs and close postoperative monitoring are used to boost the chances of a successful transplant... (MORE - missing details)
EXCERPT: . . . So far, 90 women worldwide have received uterine transplants which have resulted in 49 babies. It is important to continuously monitor the development of these babies, especially as the sole goal of the uterine transplant is for a live birth of a healthy infant.
It is particularly relevant and promising to see that the babies have grown well during pregnancy, with no evidence of growth restriction, and are meeting age-appropriate neonatal and developmental milestones for the 2 years they have been monitored.
Excitingly, the first uterine transplant in the UK took place earlier this year. The patient was a 34-year-old with a genetic condition called Mayer-Rokintansky-Küster-Hauser syndrome (MRKH), which affects 1 in 5,000 women. This means she has AUFI as she was born with ovaries but no Fallopian tubes or uterus.
She wants children, but specifically she wants to give birth and have a biological relationship with her offspring. This ruled out adoption and surrogacy.
But her sister, who doesn't have MRKH – and was born with ovaries, Fallopian tubes and a uterus – wanted to donate her uterus to help enable this. She had completed her family, having had two successful uncomplicated pregnancies and given birth to two healthy babies.
Both women had to undergo significant pre-op medical and psychological preparation to ensure their health and wellbeing were optimised and the operation could be a success. The operations for both women involved major surgery which carries its own risk.
In addition, the major concern for a recipient is the possibility of the body ‘rejecting’ the donor womb. To avoid this, anti-rejection drugs and close postoperative monitoring are used to boost the chances of a successful transplant... (MORE - missing details)