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The science of biological sex

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https://sciencebasedmedicine.org/the-sci...gical-sex/

INTRO: The debate over how best to approach people who identify as transgender or non-binary is many-layered and can be complex. Medical questions about the evidence for the safety and efficacy of specific interventions, and the ethics of treating minors, deserve thoughtful and open discussion. The optimal way to incorporate transgender athletes into competition also could benefit from a good faith debate.
Unfortunately, discussion around transgender issues suffers from at least two sources. First, it has been coopted as part of a politically-motivated culture war. This reality is exactly the opposite of thoughtful good-faith discussion. Second, for most people wrapping their head around a reality that may not conform to traditional notions of strictly binary sex and gender takes a lot or processing. Misconceptions about the basic science are rampant, and are, in fact, encouraged by the culture warriors.

Many of those who are pushing back against trans healthcare and broader acceptance are explicitly premising their position on the claim that biological sex is strictly and obviously binary. They portray themselves as taking the scientific high ground, and anyone who questions this obvious biological fact are the ones engaged in pseudoscience.

For example, in a recent article by James Lyons-Weiler (Biology is the biology is the biology, he begins:

“Most of us are born male of (sic) female. This is not our “assigned gender”: it’s our biological sex. An individuals’s sex is determined in animals (and plants) via the chromosomes one is born with.”

Wrong, right out of the gate (as I will detail below). He goes on:

“For most of us, we ARE male, or we ARE female. Unfortunately, early scientific articles conflated “gender” and “sex”, and much of society conflate them this as well. Depending on context, someone might need to know your sex (karyotype).”

He is saying that sex is strictly binary, it is entirely determined by karyotype, and it is completely distinct from gender. While these views are common, especially among those who are critical of the trans identity, they are also demonstrably scientifically wrong.

Biological Sex Is Not Binary. The notion that sex is not strictly binary is not even scientifically controversial. Among experts it is a given, an unavoidable conclusion derived from actually understanding the biology of sex. It is more accurate to describe biological sex in humans as bimodal, but not strictly binary. Bimodal means that there are essentially two dimensions to the continuum of biological sex. In order for sex to be binary there would need to be two non-overlapping and unambiguous ends to that continuum, but there clearly isn’t. There is every conceivable type of overlap in the middle – hence bimodal, but not binary.

This matters, and in fact it is the overlapping middle that is the very point of the discussion. Denying a trans identity is denying that overlapping middle. Let’s review the biology of sex to see what I mean... (MORE - details)
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