Ruffies are tranquilizer drugs rapists put into women's (and men's) drinks at bars and clubs. It causes lowering of inhibitions and blackouts lasting 7 hours. Imagine being at a bar one moment, and then the next moment waking up sitting on the curb at 6 AM with your hair dissheveled and your underwear on backwards! See how easy it is to get ruffied.
https://www.youtube.com/watch?v=GTd1647CTFs
Rohypnol:
http://www.definition-of.com/Ruffies
https://www.youtube.com/watch?v=GTd1647CTFs
Rohypnol:
http://www.definition-of.com/Ruffies