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+--- Thread: 92% Reduction in COVID-19 Mortality Rate (/thread-12816.html)
92% Reduction in COVID-19 Mortality Rate - Syne - Sep 5, 2022
Regular Use of Ivermectin as Prophylaxis for COVID-19 Led Up to a 92% Reduction in COVID-19 Mortality Rate in a Dose-Response Manner: Results of a Prospective Observational Study of a Strictly Controlled Population of 88,012 Subjects
https://www.cureus.com/articles/111851-regular-use-of-ivermectin-as-prophylaxis-for-covid-19-led-up-to-a-92-reduction-in-covid-19-mortality-rate-in-a-dose-response-manner-results-of-a-prospective-observational-study-of-a-strictly-controlled-population-of-88012-subjects
We have previously demonstrated that ivermectin used as prophylaxis for coronavirus disease 2019 (COVID-19), irrespective of the regularity, in a strictly controlled citywide program in Southern Brazil (Itajaí, Brazil), was associated with reductions in COVID-19 infection, hospitalization, and mortality rates. In this study, our objective was to determine if the regular use of ivermectin impacted the level of protection from COVID-19 and related outcomes, reinforcing the efficacy of ivermectin through the demonstration of a dose-response effect.
...
Non-use of ivermectin was associated with a 12.5-fold increase in mortality rate and a seven-fold increased risk of dying from COVID-19 compared to the regular use of ivermectin. This dose-response efficacy reinforces the prophylactic effects of ivermectin against COVID-19.
...
The regular use of ivermectin decreased hospitalization for COVID-19 by 100%, mortality by 92%, and the risk of dying from COVID-19 by 86% when compared to non-users.
Protection from COVID-19-related outcomes was observed across all levels of ivermectin use, with a notable reduction in risk of death in the over 50-year-old population and those with comorbidities. The reduction in infection rate was significant, irrespective of the level of ivermectin use. The results of this prospective observational study of a strictly controlled population of 223,128 participants reinforce the efficacy of ivermectin and the demonstration of a dose-response effect.
Did partisan journalist activists and public health officials get people killed by vilifying Ivermectin?
RE: 92% Reduction in COVID-19 Mortality Rate - C C - Sep 6, 2022
Have to admit we know someone who used it (obstinately refused the vaccine for weeks prior), and who was vulnerable to COVID. Had type I diabetes, heart problems, age, very overweight, etc. His symptoms apparently subsided without hospitalization. Only problem is that he kept testing positive for a long period, minus severe effects of the disease -- from six weeks to two months. But he took the parasite treatment during that time and did survive the virus. (Hopefully he got rid of some worms, too, if they were present.)
Possible he might have made it through without, anyway, but definitely not a healthy candidate beforehand that either friends or "informed about his medical conditions" onlookers would give much chance to weather it. Fortunately for those related to him and who know him, he did.
RE: 92% Reduction in COVID-19 Mortality Rate - Syne - Sep 6, 2022
Current CDC guidance includes the fact that anyone can test positive for a prolonged time, and can get back to work after 5 days isolation and 24 hours without a fever.
"Among COVID-19 participants, regular users were older and had a higher prevalence of type 2 diabetes and hypertension than irregular and non-users." That would seem to make the results all the more significant.
RE: 92% Reduction in COVID-19 Mortality Rate - confused2 - Sep 7, 2022
Kind'a split people up into 'All medicine is magic', 'Some medicine is magic but there is generally a link between cause and effect.' and finally 'There is no magic in medicine'.
The second comment [after the article] is ".. data is data, regardless of our beliefs." which is absolutely fair.
In the absence of any obvious connection between a drug that treats parasitic worms and a drug that might treat a viral infection a possible explanation of the result might be..
In general it is likely that the wealthy will fare better than the poor - I offer that as self-evident but will elaborate if the point is unclear. I'm guessing the drug ivermectin isn't free even in an area with a high incidence of parasitic worms so Ivermectin use can be used to classify populations into 'rich', 'not badly off' and 'abject poor'.
Basically Ivermectin won't cure worms if you haven't got them, it won't change your general rate of affluence but the ability and willingness to buy and try ivermectin might be a fair indicator of wealth even in societies without endemic parasitic worm infections.
I really don't know. I can see how data can be both good and not good at the same time.
RE: 92% Reduction in COVID-19 Mortality Rate - Syne - Sep 8, 2022
Well, some people don't understand that many drugs have off-label uses and benefits.
Some people show a lopsided skepticism for one drug while showing none for another.
The only difference seeming to be that one has the imprimatur of some authority figure.
I guess appeals to authority is one way to live.