Jun 12, 2023 03:12 PM
https://www.freethink.com/futurology/art...ctogenesis
EXCERPTS: . . . Artificial wombs would fill in the critical gap between IVF and incubators. They don’t yet exist outside of science fiction, but they’re getting closer to reality.
In 2017, researchers from Children’s Hospital of Philadelphia unveiled the “Biobag,” part of an artificial womb they are developing for prematurely born babies, known as EXTEND (“EXTrauterine Environment for Neonatal Development”).
Unlike incubators currently found in hospital NICUs, the Biobag is filled with lab-made amniotic fluid, the same liquid that surrounds a baby in the womb. Oxygen is added to the fetal bloodstream via a device attached to the umbilical cord.
“Fetal lungs are designed to function in fluid, and we simulate that environment here, allowing the lungs and other organs to develop, while supplying nutrients and growth factors,” said fetal physiologist and EXTEND developer Marcus G. Davey.
To demonstrate the Biobag, the researchers removed lamb fetuses from their mothers’ wombs at what would be the equivalent of 23-24 weeks in a human pregnancy — most human babies born at 24 weeks or earlier don’t survive, and those that do have a high chance of life-long health problems.
The animals continued developing for up to four weeks inside the Biobags, getting bigger, growing wool, and opening their eyes.
[...] A group in Europe is working on the Perinatal Life Support (PLS) system, another artificial womb designed to give extreme preemies a better shot at survival. A team from Australia and Japan, meanwhile, is developing a platform called the Ex Vivo Uterine Environment (EVE) therapy, which has already been tested with premature lambs.
All of these systems are designed to act as a bridge between the natural womb and the outside world. When will we get a device that actually replaces the womb, and what would that look like? (MORE - missing details)
Biobag ... https://youtu.be/z7OsEGT9d3o
https://youtu.be/8szWYhyZoFg
EXCERPTS: . . . Artificial wombs would fill in the critical gap between IVF and incubators. They don’t yet exist outside of science fiction, but they’re getting closer to reality.
In 2017, researchers from Children’s Hospital of Philadelphia unveiled the “Biobag,” part of an artificial womb they are developing for prematurely born babies, known as EXTEND (“EXTrauterine Environment for Neonatal Development”).
Unlike incubators currently found in hospital NICUs, the Biobag is filled with lab-made amniotic fluid, the same liquid that surrounds a baby in the womb. Oxygen is added to the fetal bloodstream via a device attached to the umbilical cord.
“Fetal lungs are designed to function in fluid, and we simulate that environment here, allowing the lungs and other organs to develop, while supplying nutrients and growth factors,” said fetal physiologist and EXTEND developer Marcus G. Davey.
To demonstrate the Biobag, the researchers removed lamb fetuses from their mothers’ wombs at what would be the equivalent of 23-24 weeks in a human pregnancy — most human babies born at 24 weeks or earlier don’t survive, and those that do have a high chance of life-long health problems.
The animals continued developing for up to four weeks inside the Biobags, getting bigger, growing wool, and opening their eyes.
[...] A group in Europe is working on the Perinatal Life Support (PLS) system, another artificial womb designed to give extreme preemies a better shot at survival. A team from Australia and Japan, meanwhile, is developing a platform called the Ex Vivo Uterine Environment (EVE) therapy, which has already been tested with premature lambs.
All of these systems are designed to act as a bridge between the natural womb and the outside world. When will we get a device that actually replaces the womb, and what would that look like? (MORE - missing details)
Biobag ... https://youtu.be/z7OsEGT9d3o
https://youtu.be/8szWYhyZoFg