Dec 23, 2021 03:07 AM
These are novel kinds of vaccines based on nanotechnology. It's based on nanoparticles that reportedly have 24 faces. Each of these faces will have the spike protein from a different coronavirus attached to it. There are two versions, with larger or smaller samples of the spike proteins. They say that each should have its advantages, and both are in clinical trials.
It's coming from the Walter Reed Army Institute of Research and it's been getting lots of press. Some of it seems kind of unbelievable, such as how it should work with all current and future covid variants, and how it should work with all other coronaviruses as well like SARS. (The common cold is caused by coronaviruses.) It might actually be true, but it would probably have to be a new modification of the vaccine with the new spike protein attached. But assuming that they can crank them out and manufacture them in quantity, it might be possible to get a new coronavirus shot every year custom designed for that year's new variants.
They say that they haven't tested it against omicron, which appeared too recently, but say it shows promise in trials against delta, earlier variants and original SARS in "non-human primates". (Presumably genetically engineered "humanized" monkeys so that these animals' otherwise completely monkey cells bear the receptors that these viruses exploit in attacking humans and thus fall prey to human diseases.)
"A series of recently published preclinical study results show that the spike ferritin nanoparticle (spfn) covid-19 vaccine developed by researchers at the Walter Reed Army Institute of Research (WRAIR) not only elicits a potent immune response but may also provide broad protection against SARS-CoV-2 variants of convern as well as other coronaviruses.
Spfn entered Phase 1 human trials in April 2021. Early analyses, expected to conclude this month, will provide insights into whether Spfn's potency and breadth, as demonstrated in preclinical trials, will carry over into humans..."
https://www.army.mil/article/252890/seri...t_strategy
It's coming from the Walter Reed Army Institute of Research and it's been getting lots of press. Some of it seems kind of unbelievable, such as how it should work with all current and future covid variants, and how it should work with all other coronaviruses as well like SARS. (The common cold is caused by coronaviruses.) It might actually be true, but it would probably have to be a new modification of the vaccine with the new spike protein attached. But assuming that they can crank them out and manufacture them in quantity, it might be possible to get a new coronavirus shot every year custom designed for that year's new variants.
They say that they haven't tested it against omicron, which appeared too recently, but say it shows promise in trials against delta, earlier variants and original SARS in "non-human primates". (Presumably genetically engineered "humanized" monkeys so that these animals' otherwise completely monkey cells bear the receptors that these viruses exploit in attacking humans and thus fall prey to human diseases.)
"A series of recently published preclinical study results show that the spike ferritin nanoparticle (spfn) covid-19 vaccine developed by researchers at the Walter Reed Army Institute of Research (WRAIR) not only elicits a potent immune response but may also provide broad protection against SARS-CoV-2 variants of convern as well as other coronaviruses.
Spfn entered Phase 1 human trials in April 2021. Early analyses, expected to conclude this month, will provide insights into whether Spfn's potency and breadth, as demonstrated in preclinical trials, will carry over into humans..."
https://www.army.mil/article/252890/seri...t_strategy